Louis Pasteur and Rabies
The story of Joseph, Louis Pasteur and
Rabies
The little boy was standing in the hallway,
crying pitifully as people bustled about him. His mother stood
nearby, wringing her hands and begging to see the famous
doctor. The boy was only nine years old and his name was Joseph
Meister.
Joseph had been playing happily near his
home in the Alsatian hills of France, when a rabid dog suddenly
attacked him. The dog would have killed him but for the
intervention of a bricklayer who drove the beast off. As it
was, little Joseph had been bitten fourteen times.
Rabies in the 1880s
The year was 1885. There was no known
treatment or cure for rabies, or hydrophobia as it was called
in humans. Hydrophobia means fear of water, but the disease
didn't actually make people afraid of water. Instead, rabies
victims would suffer a terrible thirst so that the sight of
water sometimes made them swallow. And swallowing was very
painful because one of the symptoms of the disease was throat
spasms. There were other symptoms too, all of them agonizing -
extreme restlessness, rage, shuddering, convulsions, paralysis,
choking - and eventually death. Sometimes the symptoms didn't
appear for a week or more, but when they did, it was just a
matter of time.
Little Joseph wasn't showing any symptoms
yet but there was no doubt he would. The boy had been savagely
attacked and the dog had been frothing at the mouth and acting
wild and confused. Everyone knew it was rabid. And everyone
knew what came next. The mother's eyes were red with crying and
the boy too was sobbing now - he was in pain, but more than
that he knew that everybody believed he was going to die.
The desperate mother had come to the only
man she thought might have a chance of saving her child. He had
saved many people's lives, this brilliant scientist in his
magical laboratory in Villeneuve l'Etang. Of course, none of
those people had suffered from rabies. But she had heard he was
studying rabies. Perhaps he could work yet another of his
miracles.
Louis Pasteur and his rabies
experiments
Louis Pasteur heard the commotion from his
laboratory and came out to see what the fuss was about. When he
saw the little boy and heard the mother's story, his heart was
torn in two. It was his natural impulse to do anything he could
to relieve suffering. Louis Pasteur himself had lost three
children to disease, three beautiful little girls, and he
couldn't bear the idea of not doing something to save the
little boy weeping before him. But no one had ever tried to
treat rabies before - the very treatment itself might kill the
child.
Louis Pasteur and Rabies research
Louis Pasteur had been researching rabies
for several months. Louis Pasteur knew a virus so small it
couldn't even be seen through his microscope caused it. Louis
Pasteur also knew it tended to concentrate in nerve tissue.
With that in mind, he had prepared vaccines from the spinal
cords of rabid animals, using the same principles he'd used in
making other vaccines.
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